CCLE Neuroethics Project
mapping the brain
WASHINGTON, June 3 (UPI) -- Emerging technologies that map the brain, reveal
"guilty knowledge," and expose patterns associated with disfavored behavior
raise thorny questions of law and ethics.
Three University of
Pennsylvania professors grapple with these questions in a lucid article that
appears in the June issue of the IEEE Spectrum, a monthly journal of the
Institute of Electrical and Electronic Engineers. "Bioethics and the Brain,"
although written for specialists, is refreshingly free of the jargon and bad
writing that mars so many academic publications.
Kenneth R. Foster, professor
of Bioengineering; Paul Root Wolpe, in the department of Psychiatry in the
university's Center for Bioethics; and Arthur L. Caplan, chairman of the
Department of Medical Ethics, explain that microelectronics and medical
imaging are bringing us closer to a world where mind reading is possible and
some blindness is overcome with visual prostheses -- but one in which we may
not want to live.
The authors write:
"Researchers may one day find brain activity that correlates with behavior
patterns such as tendencies toward alcoholism, aggression, pedophilia, or
Racism? United Press
International asked Caplan about that in a phone interview.
"Let's say I show you a
series of photographs of people from around the world," he replied. "And
every time a black face appears, you get a different brain pattern. (That
is, different from a baseline pattern.) I start to suspect that you are
different in your reactions to blacks than you are to others -- or whatever
the group is. ...
"Does it mean that this
bubbles to the surface and you act in racist ways? No. But subtle
differences might silently shape your behavior.
"It may make sense sometimes
to have a different reaction (to various racial types). ... But this does
give you a chance to peek in and see what's going on. ... What Freud used to
talk about as the unconscious, which I think is in pretty solid disrepute,
may get a revival from this kind of brain examination."
The article presents the case
of Nancy, a hypothetical airline pilot of the future, who arrives promptly
for her routine physical. She is asked to place her head in a large metallic
device while a video screen flashes a series of images before her eyes: the
inside of a 747 cockpit, a view of a target seen through a rifle's scope, a
chemical formula for polyester, a photo of Bill Clinton.
Later, her supervisor and a
Federal Aviation Administration official inform Nancy that her brain images
show that she might develop schizophrenia and that she has also has a
surprising familiarity with assault rifles. The FAA revokes her pilot's
license, and the airline fires her.
This fictitious scenario
alludes to technologies that already exist in their basic form. Electrical
activity in the brain can reveal the contents of a person's memory, and the
same electrical stimulation technologies that enable some deaf people to
hear can be engineered to control behavior.
These technologies have
obvious and immediate application in criminal investigation. For example, a
guilty suspect's brain might show recognition of a crime scene that an
innocent suspect would have no knowledge of.
The polygraph (lie detector)
measures physiologic responses such as heart rate, sweating, and respiration
that are only indirectly related to brain function. But the microvolt
signals of the new technologies come directly from the brain's function.
Even so, the new tests do not measure truthfulness but seek to determine
whether the subject has a particular memory.
Why, then, have the CIA, the
FBI, and the Secret Service found such techniques to be of little use in
screening for potential spies, terrorists, or other security risks?
"It's just not ready yet,"
Caplan replied. "The information that correlates complicated behavior with
brain states is not developed, but it's coming. It's a little like genomics,
where people look for correlation between a gene and, say, a predisposition
to lung cancer. ... The false positive rates and the false negative rates
are both too high right now."
The article also describes
the capabilities of functional magnetic resonance imaging, or fMRI, which
shows which parts of the brain are active by tracking changes in blood
oxygen levels. Using fMRI, Psychiatry Prof. Daniel D. Langelben of the
University of Pennsylvania found highly significant correlations between
lying and truth telling and the metabolic activity in the region of the
brain important to paying attention and monitoring errors.
MRIs and positron emission
tomography, which uses radioactive tracers to image brain activity, can
disclose subtle changes in brain structure and function that correlate to
disease -- including mental illness. But who should receive pre-symptomatic
testing or prophylactic treatment for such diseases? Relatives of those with
symptoms? Those like Nancy, with particular jobs?
And what are the legal
implications for employment screening? Caplan said an employer's attitude
might be: "I don't care if it's accurate. I took a look at your brain, and
you're not working here."
Caplan said that to forestall
predatory peddlers of "truth machines," it's not to soon to start pushing
for five things that "need to be happening" in bioethics.
The first is setting
standards for what is ready to be used in the marketplace and what is not.
Because this involves issues of accuracy and error rates, scientists rather
than politicians should set the standards, he said.
Second, Caplan said, "We need
to have some agreement about the admissibility of this evidence in court."
Judges, prosecutors and defense attorneys should be introduced to the
technology and confer. A defense attorney might ask the circumstances under
which he could say: "My client may have done it, but he has a bad amygdala
(a part of the brain that controls fear and arousal), so don't punish him."
The new technologies also could be used in considering the suitability of an
inmate for parole.
A third ethical issue is that
of consent. "Must consent be given to this sort of brain testing?" Caplan
asked. The professor presumes consent, but said compulsory testing might be
necessary for national security reasons or for certain types of job
screening. The conditions for these exceptions must be explicit, however.
Caplan was asked if
withholding consent would be used against a defendant in a criminal case. He
agreed that such a refusal would affect a jury regardless of a judge's
instructions. The professor said he doesn't care how society establishes its
standards, "but let's set the moral framework up right now." The courtroom
is not the place to argue, he told UPI.
He said this became clear in
determining what data are sufficient to establish paternity. "We had to hack
it out in court, case by case." Experts could have set standards and
guidelines, Caplan said.
A fourth ethical issue is
access. "If you're going to build pictures of the brain, you can also build
data bases just like you do genetic ones," Caplan said. "We could have
pictures of everybody's head on file. Is that a good idea? Who would run it?
How would you get access to such a thing? Somebody may say, 'I want to take
a picture of my head to show you that I'm innocent, but it may cost
something.' Will it be just a gimmick for the rich? Should we insist that
everybody have fair access if it comes up for legal matters?"
Fifth, and most
controversial, are the ethical considerations surrounding the testing of
"Parents might say: 'I want
to find out if little Johnny is good at the violin. I'm not going to waste
lessons on him if he's got no natural aptitude,'" Caplan told UPI.
"Just as there's an
educational testing juggernaut, there could easily be a brain testing
juggernaut tomorrow." Rules should be established about what can and can't
be done with children, he said.
"Worried parents -- the
worried well -- are going to be falling all over themselves to get this
stuff done with their kids. This is the gift to neurotic parents everywhere,
especially wealthy neurotic parents. Why waste your time getting your kid
ready for that fancy Manhattan nursery school if he's not going to get into
"Can (brain) tests really
predict all that? Probably not. But you can become very reductionistic about
it and think that your fate is your brain. In some ways, of course, it is.
But that doesn't mean you can't change things with learning and environment.
Yes, it is predictive, but we don't want to sell it as 100 percent
"So doctors and psychologists
will have important questions about when they will test, why they will test,
and how they will counsel."
Caplan was asked if he could
envision a coffe-table book that showed the brain patterns of future
Tolstoys, Mozarts, and Einsteins. Parents would try to match up little
Johnny to see where he fits.
"Bet on it," Caplan said.
story ran in the Washington Times on 6/3/2003.
2003 Washington Times.